Martin Egli holds an appointment as Professor of Biochemistry at Vanderbilt University. He received his diploma in Chemistry from ETH Zürich and his PhD in chemical crystallography and stereochemistry with Jack Dunitz and Vladimir Prelog at the same institution. After postdoctoral studies with Alexander Rich in the Department of Biology at MIT and a lectureship at ETHZ, he spent five years as Assistant Professor at Northwestern University before moving to Vanderbilt in 2000. He was a visiting professor in the Departments of Chemistry at Seoul National University (Seoul, Korea) and the University of Oxford (Oxford, UK). His research interests include the 3D structures of DNA, RNA, and artificial pairing systems (XNA), chemical modification and conjugation of siRNA therapeutics, trans-lesion DNA polymerase-DNA adduct interactions, the structure and function of circadian clocks, the structure and activity of steroidogenic cytochrome P450s, and SAR of protein/enzyme-ligand interactions. Research in the Egli lab is supported by the US National Institutes of Health, the US National Science Foundation, and Alnylam Pharmaceuticals.