Daniela Rhodes, FRS, is an internationally recognized for crystallizing the nucleosome core – a major scientific breakthrough in the 1970s – and for her structural work on chromatin, telomeres and transcription factors. She determined the structures of a number of important protein-DNA complexes involved in transcription, such as zinc-fingers and nuclear hormone receptors.
She has provided some of the first structural information on telomeric proteins, such as yeast Rap1p and human TRF1 and TRF2 and their complexes with DNA. Throughout her career she has made many contributions to the understanding of chromatin structure and function. Her research continues to focus on understanding how the structure of chromatin is involved in transcriptional regulation and how telomeres are involved in preserving chromosome integrity. She worked at the Laboratory of Molecular Biology (MRC-LMB) in Cambridge, UK for over 30 years. She has been a Visiting Professor at “La Sapienza” in Rome and at the Rockefeller University in New York. She has published over 100 scientific papers and book chapters that have been cited more than 16,000 times. She is a Member of EMBO and Academia Europaea.