Institute of Pharmacy and Molecular Biotechnology
69120 Heidelberg, Germany
After obtaining his degree from the School of Pharmacy, Freie Universität Berlin, Stefan Wölfl continued his studies at the Institute of Biochemistry and received a PhD in biochemistry from Freie Universität Berlin. In addition to working in academic research he also worked as a certified pharmacist in applied pharmacy. He continued his research studies as a postdoctoral researcher in Alexander Rich lab at MIT studying left handed Z-DNA in living cells. In 1993 Stefan Wölfl became junior group leader at the Hans-Knöll-Insitute of Natural Product Research, Jena, Germany, focusing on the development of new technologies to study gene expression and cellular signaling. In Jena we became co-founder of biotech and diagnostics company “Clondiag Chip Technologies”, Jena, now part of Abbott diagnostics. For his contribution and work on chip technologies he was co-recipient of the Thüringer-Forschungspreis 1998. In 1999 he received habilitation (Dr. habil.) from the Friedrich-Schiller-University Jena and continued his career at the University Hospital Jena, establishing a Molecular Biology research group for biomedical research focusing on genetic engineering for the development of cellular biosensors and gene expression analysis. Now, for 20 years since 2003, he is Professor for Pharmaceutical Biology, Bioanalytics and Molecular Biology at the Institute of Pharmacy and Molecular Biotechnology (IPMB) of Heidelberg University. The present focus of his research lab is the role of cell metabolism as key player in the development of disease and as factor influencing biological activity of drug compounds. His group also developed a platform for the rapid analysis of protein modifications in signal transduction and established liver kidney organ-on-chip technologies for live on-line drug activity monitoring. He is also responsible for various teaching activities in the Pharmacy and Molecular Biotechnology programs of Heidelberg University.